Bitter Taste Receptors can kill cancer?
And a topical anesthetic can activate it. PREMIUM CONTENT subscriber access
Ectopic olfactory/taste receptors are found throughout the human body. In particular, the Bitter ‘taste’ receptor [T2] abides in sinuses and lung linings. They are also involved in innate immunity, thyroid function, cardiac physiology, and sperm.
I described these receptors in my past newsletters:
Is this how/why aromatherapy works?
Past newsletters talked about using smell tests for dementia diagnosis, but also for covid infections. And there was the one on nasal exosomes sending stuff into the brain via the olfactory organ. Hmmm … nose - brain - immune linked. But what if those olfactory chemosensing receptors were also found outside the CNS and nasal cribriform plate - actually,
More Lung Learnings
Past newsletters described the ectopic olfactory receptors found throughout the body. In particular, the Bitter ‘taste’ receptor [T2] abides in sinuses and lung linings. Now recent lab work is building on that knowledge to exploit the receptor for therapeutic development.
Now we have a new article reporting use of this cellular route to induce cell death in squamous cell cancers of the head and neck.
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