NVS is using Molecular Partners' DARPins to make SARS-CoV-2 therapeutics

What in the world are DARPins? PREMIUM CONTENT

DARPins are so cool, that I put them in the plot of my med thriller, Vampire Chimeras, back in 2013. (I also found out about and used CRISPR/cas in insects’ immunity, but that’s a story for another time.) In the novel, I used these protein scaffolds to make a vaccine to fight dengue fever. Now, lo and behold! IRL, Novartis/Molecular Partners collaboration is making an antiviral therapeutic — for SARS-CoV-2.

Ensovibep (MP0420) binding to COVID-19 spike protein. HSA = human serum albulmin