Mobilizing glymph to manage migraine

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“Migraine is a complex neurological disease that is characterized by attacks lasting between 4 hours and 3 days, and is characterized primarily by a moderate‐to‐severe paroxysmal, unilateral headache that is aggravated by movement, and may be accompanied by symptoms of photophobia, phonophobia, osmophobia, allodynia, pain on movement, and nausea and vomiting.”

“A person with migraine has a hypersensitive nervous system. It overreacts to stimuli, causing a wave of brain activity that leads to a headache and other symptoms. The trigeminal nerve is involved in attacks for almost all people with migraine.”

In my past newsletter, Deep Dive into Dementia: Some surprising therapeutics proposed, I described the brain’s lymphatic drainage system and its role in neurodegenerative diseases:

“The big news coming just a year after this, was the discovery of brain’s lymphatic system - glymphatics. It was aptly named, “the garbage truck of the brain” because it flushed out the toxins floating in the brain parenchyma, through the neuropil, with each heart beat arterial pulse. Their results show that during sleep a plumbing system may open, letting fluid flow rapidly through the brain. The glymphatic system helps control the flow of cerebrospinal fluid, long thought to be a glial/astrocyte function.”

New research now shows that headache relief comes when the glymphatics open and drain out their contents.